IQUAD-2300
iQuad 2300 Series ICP-MS
A single quadrupole ICP-MS from HanSel for measuring elements down to ultratrace levels. Its 7-port system can cut analysis time per sample by up to 50%, and the instrument can be started, scheduled or shut down from a phone app.
Key Features
- Food and agriculture: Supporting food safety regulation, nutritional research and research on metal toxicity in food
- Environmental: Heavy metals in water, soil and air; solid waste; and environmental emission monitoring
- Pharma: Helping manufacturers meet USP/EP/CP requirements, including heavy metal testing in traditional Chinese medicines (TCM)
- Material: Geology and minerals, metals and new materials, electronics, semiconductors, photovoltaics and battery materials
- Biological: Research on proteins, nucleic acids and single cells; isotope-specific radiolabelling in immunology; nano-particle analysis
- Energy and chemical: Petrochemicals, alternative energy research and specialized chemical materials
Technical Specifications
General
- Type: Single quadrupole ICP-MS
- Manufacturer: HanSel
- Commercial Launch: July 2023
- Software: iTrace, with a one-button "Get Start", auto-tune and comprehensive quality control
- Regulatory Compliance: FDA 21CFR Part 11 compliant (user access control, e-signature and audit trail)
- Remote Operation: Through a phone app, the instrument can be started on a schedule or remotely, and the plasma is switched off automatically
RF Generator and Plasma
- RF Generator: 27.12 MHz, digitally synthesised with variable-frequency impedance matching; no matching box and maintenance-free
- Torch: Virtual Grounding design, no shield torch
- Plasma: Easy switching between cold and hot plasma; includes Plasma TV
- Interface: Water-cooled sampling and skimmer cones, with nickel and platinum options
Sample Introduction
- Valve: High-speed 7-port valve. Sample loading and rinsing run at the same time, cutting analysis time per sample by up to 50% and using less argon
- Nebulizer: Standard concentric; compatible with mainstream nebulizers (high-purity quartz, PTFE, PFA)
- Spray Chamber: Peltier-cooled cyclonic chamber (standard) that keeps signal drift down; Scott double-pass optional
- Peristaltic Pump: 4 channels, 12 rollers, adjustable speed
- Automatic Alignment: Automatic X-Y-Z alignment and sampling depth optimization
- Compatibility: Autosamplers and auto-dilution devices (CETAC, ESI)
Collision/Reaction Cell and Analyzer
- Collision/Reaction Cell: High-transmission hexapole with axial acceleration
- Interference Removal: Two modes, KED (Kinetic Energy Discrimination) and SER (Selected Exothermic Reaction), to remove polyatomic interferences
- Mass Analyzer: Long quadrupole driven by a digitally synthesised RF generator; no custom quadrupole tuning needed
- Ion Optics: Dual off-axis ion path that removes neutral particles, giving a lower analytical background
Detector
- Detector: High-sensitivity electron multiplier with analog/pulse dual mode
- Linear Dynamic Range: More than 10¹¹ (with electronic dilution)
- Minimum Integration Time: 10 µs
- Electronic Dilution: Applied per isotope, so ultratrace elements and elements at thousands of ppm can be measured together in one sample
Performance
- Long-term Stability: 4-hour signal drift with RSD < 3%
- Difficult Matrices: Online aerosol dilution; stable on saturated saline matrices
- Accuracy Check: Tested with GBW E 080684 rice powder CRM, spike recovery 93–107%
Applications and Use Cases
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Biochemistry & Life Sciences
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Clinical Diagnostics
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Environmental & Water Science
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Food & Beverage
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Pharmaceuticals & Medicines